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CTDP1 Antibody - C-terminal region : Biotin (ARP65744_P050-Biotin)

Selected Variant

ARP65744_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) phosphatase, subunit 1

Gene Aliases

FCP1, CCFDN

Gene ID

9150

Swiss Prot

Q9Y5B0

Accession Number

NP_430255

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human CTDP1

Target

This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF, and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II), making it available for initiation of gene expression. Mutations in this gene are associated with congenital cataracts, facial dysmorphism and neuropathy syndrome (CCFDN) . Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Partner Proteins

UBC; CDK9; UPP1; PPP2CA; PPP1CA; POLR2A; POLR2C; GRK5; ELP2; ELP3; SUMO2; PRKDC; CDK8; CDK7; INTS8; MED15; MED4; INTS6; INTS1; INTS7; MED16; MED6; MED24; MED7; MED26; MED17; MED23; MED14; MED1; MED8; MED25; INTS3; POLR2J; ERH; POLR2B; STK38; PRMT5; HIST1H

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 100%; Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 85%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

93kDa

Shipping Conditions

Wet Ice

Protein Length

867

NCBI Gene Symbol

CTDP1

NCBI GB Accession Number

CTDP1

Host or Source

Rabbit

Protein Name

RNA polymerase II subunit A C-terminal domain phosphatase

Nucleotide Accession Number

NM_048368

Peptide Sequence

AHAPDKEPELGGQEEGERDGLCGLGNGCADRKEAETESQNSELSGVTAGE

Subunit

A C-terminal domain phosphatase

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