ARPC1B Antibody - middle region: FITC (ARP65735_P050-FITC)
Product Specifications
Gene Name
Actin related protein 2/3 complex subunit 1B
Gene Aliases
ARC41, IMD71, PLTEID, p40-ARC, p41-ARC
Gene ID
10095
Swiss Prot
O15143
Accession Number
NP_005711
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of Human ARPC1B
Target
This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase.
Partner Proteins
SUMO2; UBC; SUMO1; NEDD8; BTF3L4; C14orf142; IPO11; TPRKB; PDCD4; ANP32B; ARPC2; ACTR2; ACTR3; ARPC3; ARPC4; ARPC5; TOM1L1; ANP32A; VBP1; UBE3A; TPD52L2; TPD52; RPA2; RANGAP1; PRKACB; PPP2R5D; METTL1; HSF1; DR1; DHPS; CALU; CALR; AARS; SRPK2; PAN2; WASL
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
41kDa
Shipping Conditions
Wet Ice
Protein Length
372
NCBI Gene Symbol
ARPC1B
Protein Name
Actin-related protein 2/3 complex subunit 1B
Nucleotide Accession Number
NM_005720
Curated Selection
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