ARPC1B Antibody - middle region : Biotin (ARP65735_P050-Biotin)

Product Specifications

Gene Name

Actin related protein 2/3 complex subunit 1B

Gene Aliases

ARC41, IMD71, PLTEID, p40-ARC, p41-ARC

Gene ID

10095

Swiss Prot

O15143

Accession Number

NP_005711

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the middle region of Human ARPC1B

Target

This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase.

Partner Proteins

SUMO2; UBC; SUMO1; NEDD8; BTF3L4; C14orf142; IPO11; TPRKB; PDCD4; ANP32B; ARPC2; ACTR2; ACTR3; ARPC3; ARPC4; ARPC5; TOM1L1; ANP32A; VBP1; UBE3A; TPD52L2; TPD52; RPA2; RANGAP1; PRKACB; PPP2R5D; METTL1; HSF1; DR1; DHPS; CALU; CALR; AARS; SRPK2; PAN2; WASL

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.