SPG21 Antibody - C-terminal region : Biotin (ARP65714_P050-Biotin)
Selected Variant
ARP65714_P050-Biotin
Size: 100 µL
Product Specifications
Gene Aliases
MAST, ACP33, GL010, ABHD21, BM-019
Gene ID
51324
Swiss Prot
Q9NZD8
Accession Number
NP_057714
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human SPG21
Target
The protein encoded by this gene was identified by a two-hybrid screen using CD4 as the bait. It binds to the hydrophobic C-terminal amino acids of CD4 which are involved in repression of T cell activation. The interaction with CD4 is mediated by the noncatalytic alpha/beta hydrolase fold domain of this protein. It is thus proposed that this gene product modulates the stimulatory activity of CD4. At least three different transcript variants encoding two different isoforms have been found for this gene.
Partner Proteins
INCA1; SPRED2; DTX3L; CMTM5; TRIM9; DTX2; REEP6; FAM114A1; ATPAF2; EFHC2; CCDC33; CCDC102B; TRIM54; AGTRAP; CTPS2; S100B; PRPS1; KRT15; CRYAA; TRIM23; CUTC; ARL6IP1; IKZF3; MID2; RABAC1; TFG; TRAF2; TRAF1; TCF12; TCF4; UBC; GSK3A; DHX40; YLPM1; HMGCS1; AK
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
35kDa
Shipping Conditions
Wet Ice
Protein Length
308
NCBI Gene Symbol
SPG21
NCBI GB Accession Number
SPG21
Host or Source
Rabbit
Protein Name
Maspardin
Nucleotide Accession Number
NM_016630
Peptide Sequence
IPVTIMDVFDQSALSTEAKEEMYKLYPNARRAHLKTGGNFPYLCRSAEVN
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