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BCAS1 Antibody - C-terminal region : HRP (ARP65409_P050-HRP)

Selected Variant

ARP65409_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Breast carcinoma amplified sequence 1

Gene Aliases

AIBC1, NABC1, PMES-2

Gene ID

8537

Swiss Prot

O75363

Accession Number

NP_003648

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C terminal region of human BCAS1

Target

This gene resides in a region at 20q13 which is amplified in a variety of tumor types and associated with more aggressive tumor phenotypes. Among the genes identified from this region, it was found to be highly expressed in three amplified breast cancer cell lines and in one breast tumor without amplification at 20q13.2. However, this gene is not in the common region of maximal amplification and its expression was not detected in the breast cancer cell line MCF7, in which this region is highly amplified. Although not consistently expressed, this gene is a candidate oncogene. Two transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

DYNLL1; BCAS1; RUVBL2

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity purified

Concentration

0.5 mg/ml

Homology

Cow: 79%; Dog: 92%; Horse: 100%; Human: 100%; Pig: 100%; Rat: 79%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

62 kDa

Shipping Conditions

Wet Ice

Protein Length

584

NCBI Gene Symbol

BCAS1

NCBI GB Accession Number

BCAS1

Host or Source

Rabbit

Protein Name

Breast carcinoma-amplified sequence 1

Nucleotide Accession Number

NM_003657.2

Peptide Sequence

GAPQKGKEGSSKDKKSAAEMNKQKSNKQEAKEPAQCTEQATVDTNSLQNG

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