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SUCLG1 Antibody - C-terminal region : HRP (ARP65389_P050-HRP)

Selected Variant

ARP65389_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Succinate-CoA ligase, alpha subunit

Gene Aliases

GALPHA, MTDPS9, SUCLA1

Gene ID

8802

Swiss Prot

P53597

Accession Number

NP_003840

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human SUCLG1

Target

This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depletion.

Partner Proteins

SUMO2; ECT2; S100A16; SEPT11; RIF1; SEPT9; SELENBP1; SUCLA2; SUCLG2; SDHA; OXCT1; CHMP1B; UBC; MYC

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 86%; Zebrafish: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

33kDa

Shipping Conditions

Wet Ice

Protein Length

346

NCBI Gene Symbol

SUCLG1

NCBI GB Accession Number

SUCLG1

Host or Source

Rabbit

Protein Name

Succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial

Nucleotide Accession Number

NM_003849

Peptide Sequence

MGHAGAIIAGGKGGAKEKISALQSAGVVVSMSPAQLGTTIYKEFEKRKML

Subunit

Alpha, mitochondrial

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