NANS Antibody - C-terminal region : Biotin (ARP65353_P050-Biotin)
Selected Variant
ARP65353_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
N-acetylneuraminic acid synthase
Gene Aliases
SAS, SEMDG, SEMDCG, HEL-S-100
Gene ID
54187
Swiss Prot
Q9NR45
Accession Number
NP_061819
Host
Rabbit
Reactivity
Human, Rat, Cow, Dog, Pig, Rabbit
Target
This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.
Partner Proteins
SUMO2; UBC; NEDD8; ATG3; SMEK2; CNDP2; POLE3; DAK; NPEPPS; SLC9A3R1; RPLP2; MVD; PDIA3; GBP2; EIF4E; CKB; ASS1; BAG3; HSP90AB1; HSP90AA1; PCMT1; CRK; RAD23B; DDA1
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 86%; Dog: 79%; Human: 100%; Pig: 86%; Rabbit: 79%; Rat: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
40kDa
Shipping Conditions
Wet Ice
Protein Length
359
NCBI Gene Symbol
NANS
NCBI GB Accession Number
NANS
Host or Source
Rabbit
Protein Name
Sialic acid synthase
Nucleotide Accession Number
NM_018946
Peptide Sequence
DMLTVKVGEPKGYPPEDIFNLVGKKVLVTVEEDDTIMEELVDNHGKKIKS
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