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NANS Antibody - C-terminal region : Biotin (ARP65353_P050-Biotin)

Selected Variant

ARP65353_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

N-acetylneuraminic acid synthase

Gene Aliases

SAS, SEMDG, SEMDCG, HEL-S-100

Gene ID

54187

Swiss Prot

Q9NR45

Accession Number

NP_061819

Host

Rabbit

Reactivity

Human, Rat, Cow, Dog, Pig, Rabbit

Target

This gene encodes an enzyme that functions in the biosynthetic pathways of sialic acids. In vitro, the encoded protein uses N-acetylmannosamine 6-phosphate and mannose 6-phosphate as substrates to generate phosphorylated forms of N-acetylneuraminic acid (Neu5Ac) and 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (KDN), respectively; however, it exhibits much higher activity toward the Neu5Ac phosphate product. In insect cells, expression of this gene results in Neu5Ac and KDN production. This gene is related to the E. coli sialic acid synthase gene neuB, and it can partially restore sialic acid synthase activity in an E. coli neuB-negative mutant.

Partner Proteins

SUMO2; UBC; NEDD8; ATG3; SMEK2; CNDP2; POLE3; DAK; NPEPPS; SLC9A3R1; RPLP2; MVD; PDIA3; GBP2; EIF4E; CKB; ASS1; BAG3; HSP90AB1; HSP90AA1; PCMT1; CRK; RAD23B; DDA1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 86%; Dog: 79%; Human: 100%; Pig: 86%; Rabbit: 79%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

40kDa

Shipping Conditions

Wet Ice

Protein Length

359

NCBI Gene Symbol

NANS

NCBI GB Accession Number

NANS

Host or Source

Rabbit

Protein Name

Sialic acid synthase

Nucleotide Accession Number

NM_018946

Peptide Sequence

DMLTVKVGEPKGYPPEDIFNLVGKKVLVTVEEDDTIMEELVDNHGKKIKS

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