ABRAXAS1 Antibody - C-terminal region : FITC (ARP65320_P050-FITC)
Selected Variant
ARP65320_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Abraxas 1, BRCA1 A complex subunit
Gene Aliases
ABRA1, CCDC98, FAM175A
Gene ID
84142
Swiss Prot
Q6UWZ7
Accession Number
NP_620775
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the C terminal region of human FAM175A
Target
This gene encodes a protein that binds to the C-terminal repeats of breast cancer 1 (BRCA1) through a phospho-SXXF motif. The encoded protein recruits ubiquitin interaction motif containing 1 protein to BRCA1 protein and is required for DNA damage resistance, DNA repair, and cell cycle checkpoint control. Pseudogenes of this gene are found on chromosomes 3 and 8. Alternative splicing results in multiple transcript variants.
Partner Proteins
FANCG; UIMC1; BRCA1; BRCC3; BABAM1; UBC; SUMO2; PAXIP1; MDC1; BARD1; BRE; HSPA4
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity purified
Concentration
0.5 mg/ml
Homology
Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
47 kDa
Shipping Conditions
Wet Ice
Protein Length
409
NCBI Gene Symbol
ABRAXAS1
NCBI GB Accession Number
ABRAXAS1
Host or Source
Rabbit
Protein Name
BRCA1-A complex subunit Abraxas 1
Nucleotide Accession Number
NM_139076.2
Peptide Sequence
TPQIIKHKALDLDDRWQFKRSRLLDTQDKRSKADTGSSNQDKASKMSSPE
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