NELFB Antibody - N-terminal region : FITC (ARP65310_P050-FITC)
Selected Variant
ARP65310_P050-FITC
Size: 100 µL
Product Specifications
Gene Name
Negative elongation factor complex member B
Gene Aliases
COBRA1, NELF-B
Gene ID
25920
Swiss Prot
Q8WX92
Accession Number
NP_056271
Host
Rabbit
Reactivity
Human
Immunogen
The immunogen is a synthetic peptide directed towards the N terminal region of human COBRA1
Target
NELFB is a subunit of negative elongation factor (NELF), which also includes NELFA (WHSC2; MIM 606026), either NELFC or NELFD (TH1L; MIM 605297), and NELFE (RDBP; MIM 154040) . NELF acts with DRB sensitivity-inducing factor (DSIF), a heterodimer of SPT4 (SUPT4H1; MIM 603555) and SPT5 (SUPT5H; MIM 602102), to cause transcriptional pausing of RNA polymerase II (see MIM 180660) (Narita et al., 2003 [PubMed 12612062]) .[supplied by OMIM, Mar 2008]
Partner Proteins
UBC; ABCF1; DIMT1; EDC4; IGF2BP3; SYNCRIP; EIF2B2; EIF2B3; EIF3C; YBX3; RPL23A; RFC4; PTBP1; PA2G4; YBX1; NMT1; MRE11A; ILF2; HNRNPU; FKBP3; DHX9; DDX1; KHDRBS3; DENR; YWHAB; MGST1; HSPA9; Dlg4; POLR2C; NELFB; SUPT5H; POLR2A; ATP1A1; ALDH3A2; NELFCD; CCT8
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Yeast: 90%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
66 kDa
Shipping Conditions
Wet Ice
Protein Length
580
NCBI Gene Symbol
NELFB
NCBI GB Accession Number
NELFB
Host or Source
Rabbit
Protein Name
Negative elongation factor B
Nucleotide Accession Number
NM_015456.4
Peptide Sequence
NCTEPLKAIEQFQTENGVLLPSLQSALPFLDLHGTPRLEFHQSVFDELRD
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