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SRGAP2 Antibody - N-terminal region: HRP (ARP65277_P050-HRP)

Product Specifications

Gene Name

SLIT-ROBO Rho GTPase activating protein 2

Gene Aliases

FNBP2, SRGAP3, SRGAP2A, ARHGAP34

Gene ID

23380

Swiss Prot

P0DJJ0

Accession Number

NP_001258799

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the N terminal region of human SRGAP2

Target

This locus encodes a member of the SLIT-ROBO Rho GTPase activating protein family. The encoded protein stimulates GTPase activity of Rac1, and plays a role in cortical neuron development. This locus has several paralogs on human chromosome 1 resulting from segmental duplication. While this locus itself is conserved among various species, the paralogs are found only in the genus Homo, and not in the genomes of non-human great apes. Alternatively spliced transcript variants have been described for this locus.

Partner Proteins

UBC; PPP2R1A; YWHAB; YWHAE; UBD; FASLG; HERC2; EXOC1; DISC1; YWHAG; MYO1G; YLPM1; ATAD3A; ITSN2; SLC25A12; WIPF1; WAS; DIAPH1; ROBO1

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity purified

Concentration

0.5 mg/mL

Homology

Cow: 87%; Dog: 100%; Guinea Pig: 87%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 87%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

53 kDa

Shipping Conditions

Wet Ice

Protein Length

459

NCBI Gene Symbol

SRGAP2

Protein Name

SLIT-ROBO Rho GTPase-activating protein 2

Nucleotide Accession Number

NM_001170637.3

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