SNX6 Antibody - middle region : Biotin (ARP65275_P050-Biotin)

This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associates with the long isoform of the leptin receptor, the transforming growth factor-beta family of receptor serine-threonine kinases, and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor. This protein may form oligomeric complexes with family member proteins through interactions of both the PX domain and the coiled coil regions of the molecules. Translocation of this protein from the cytoplasm to the nucleus occurs after binding to proviral integration site 1 protein. This gene results in two transcripts encoding two distinct isoforms.

UBC; FAM129B; VPS35; VPS29; RTF1; ATG7; TSNAX; TSN; STAT1; SNX2; SHMT2; SHMT1; PAWR; H3F3A; GTF2A1; ATP6V1C1; APEH; ANP32E; CSNK2A2; SNX1; BRCA1; PHLPP1; COIL; GIT1; ELAVL1; NDEL1; DISC1; TNIK; CALM1; TPT1; SNX6; SNX4; BMPR1B; ACVR2B; ACVRL1; LEPR; TGFBR2

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.