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PDE6G Antibody - N-terminal region : FITC (ARP65136_P050-FITC)

Selected Variant

ARP65136_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Phosphodiesterase 6G, cGMP-specific, rod, gamma

Gene Aliases

PDEG, RP57

Gene ID

5148

Swiss Prot

P18545

Accession Number

NP_002593

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Target

This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants.

Partner Proteins

L3MBTL3; BHLHE40; FNBP1; PDE6G; TRIP10; DNM2; MAPK3; SRC; GNAO1; ADRBK1; GRB2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

10kDa

Shipping Conditions

Wet Ice

Protein Length

87

NCBI Gene Symbol

PDE6G

NCBI GB Accession Number

PDE6G

Host or Source

Rabbit

Protein Name

Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma

Nucleotide Accession Number

NM_002602

Peptide Sequence

GPVTPRKGPPKFKQRQTRQFKSKPPKKGVQGFGDDIPGMEGLGTDITVIC

Subunit

Gamma

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