EIF3I Antibody - middle region : Biotin (ARP64825_P050-Biotin)

EIF3I is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC) . The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.

HUWE1; UBC; SUMO2; SUMO3; RNF2; rev; EIF3G; HECW2; EIF3B; CDK18; TARDBP; NPM1; ICAM1; CD81; IGSF8; PAN2; EIF3D; VCAM1; ITGA4; METTL18; gag-pol; DDX3X; PAXIP1; LIG4; EIF3L; EIF3K; EIF3M; EIF3H; EIF3F; EIF3C; EIF3A; EIF3E; CUL3; CDK2; YWHAZ; SIRT7; ARRB1; R

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.