PACS1 Antibody - C-terminal region : HRP (ARP64806_P050-HRP)
Selected Variant
ARP64806_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
Phosphofurin acidic cluster sorting protein 1
Gene Aliases
SHMS, MRD17
Gene ID
55690
Swiss Prot
Q6VY07
Accession Number
AAH55288
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Target
This gene encodes a protein with a putative role in the localization of trans-Golgi network (TGN) membrane proteins. Mouse and rat homologs have been identified and studies of the homologous rat protein indicate a role in directing TGN localization of furin by binding to the protease's phosphorylated cytosolic domain. In addition, the human protein plays a role in HIV-1 Nef-mediated downregulation of cell surface MHC-I molecules to the TGN, thereby enabling HIV-1 to escape immune surveillance.
Partner Proteins
UBC; GGA3; CSNK2A1; FGFR1OP; PPP2CA; VAMP4; CLCN7; PPP2CB; PKD2; JUN; IGF2R; FURIN; TRPV4; nef
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
62kDa
Shipping Conditions
Wet Ice
Protein Length
575
NCBI Gene Symbol
PACS1
NCBI GB Accession Number
PACS1
Host or Source
Rabbit
Protein Name
Phosphofurin acidic cluster sorting protein 1
Nucleotide Accession Number
NM_018026
Peptide Sequence
ALAIVGSPNSPYGDVIGLQVDYWLGHPGERRREGDKRDASSKNTLKSVFR
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