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CABLES1 Antibody - C-terminal region : HRP (ARP64758_P050-HRP)

Selected Variant

ARP64758_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Cdk5 and Abl enzyme substrate 1

Gene Aliases

CABL1, IK3-1, CABLES, HsT2563

Gene ID

91768

Swiss Prot

Q8TDN4

Accession Number

NP_001094089

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human CABLES1

Target

This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers.Multiple transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

CDK5; ALB; TDRD7; CCNA1; TP73; TP53; ABL1; CCNE1; CDK3

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

67kDa

Shipping Conditions

Wet Ice

Protein Length

633

NCBI Gene Symbol

CABLES1

NCBI GB Accession Number

CABLES1

Host or Source

Rabbit

Protein Name

CDK5 and ABL1 enzyme substrate 1

Nucleotide Accession Number

NM_001100619

Peptide Sequence

IRSLKREMRKLAQEDCGLEEPTVAMAFVYFEKLALKGKLNKQNRKLCAGA

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