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TXNRD3 Antibody - N-terminal region : HRP (ARP64748_P050-HRP)

Selected Variant

ARP64748_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Thioredoxin reductase 3

Gene Aliases

TGR, TR2, TRXR3, TR2IT1, TXNRD3NB, TXNRD3IT1, TXNRD3NT1

Gene ID

114112

Swiss Prot

Q86VQ6

Accession Number

NP_443115

Host

Rabbit

Reactivity

Human, Mouse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the N-terminal region of Human TXNRD3

Target

This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein catalyzes the reduction of thioredoxin, and is implicated in the defense against oxidative stress. It contains a selenocysteine (Sec) residue (which is essential for catalytic activity), encoded by a UGA codon, at the penultimate C-terminal position. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

UBC

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%; Mouse: 86%; Rabbit: 86%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

70kDa

Shipping Conditions

Wet Ice

Protein Length

643

NCBI Gene Symbol

TXNRD3

NCBI GB Accession Number

TXNRD3

Host or Source

Rabbit

Protein Name

Thioredoxin reductase 3

Nucleotide Accession Number

NM_052883

Peptide Sequence

LSPPGRRARLSSPGPSRSSEAREELRRHLVGLIERSRVVIFSKSYCPHST

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