TXNRD3 Antibody - N-terminal region : HRP (ARP64748_P050-HRP)
Selected Variant
ARP64748_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
Thioredoxin reductase 3
Gene Aliases
TGR, TR2, TRXR3, TR2IT1, TXNRD3NB, TXNRD3IT1, TXNRD3NT1
Gene ID
114112
Swiss Prot
Q86VQ6
Accession Number
NP_443115
Host
Rabbit
Reactivity
Human, Mouse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Human TXNRD3
Target
This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein catalyzes the reduction of thioredoxin, and is implicated in the defense against oxidative stress. It contains a selenocysteine (Sec) residue (which is essential for catalytic activity), encoded by a UGA codon, at the penultimate C-terminal position. The 3' UTR of Sec-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Partner Proteins
UBC
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Human: 100%; Mouse: 86%; Rabbit: 86%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
70kDa
Shipping Conditions
Wet Ice
Protein Length
643
NCBI Gene Symbol
TXNRD3
NCBI GB Accession Number
TXNRD3
Host or Source
Rabbit
Protein Name
Thioredoxin reductase 3
Nucleotide Accession Number
NM_052883
Peptide Sequence
LSPPGRRARLSSPGPSRSSEAREELRRHLVGLIERSRVVIFSKSYCPHST
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