SUCLA2 Antibody - C-terminal region : HRP (ARP64675_P050-HRP)
Selected Variant
ARP64675_P050-HRP
Size: 100 µL
Product Specifications
Gene Name
Succinate-CoA ligase, ADP-forming, beta subunit
Gene Aliases
A-SCS, A-BETA, MTDPS5, LINC00444, SCS-betaA
Gene ID
8803
Swiss Prot
Q9P2R7
Accession Number
NP_003841
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Target
Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6.
Partner Proteins
FAM9B; CMTM5; AGTRAP; ARL6IP1; SUMO2; UBC; gag-pol; MRPL12; RBM4; OXCT1; IDH3A; AGFG1; S100A16; NADK2; HPDL; NIT2; SEC22B; GRHPR; SUCLG1; SDHA; RRM1; AGO4; ICT1; PSMD14; ALAS2
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 86%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Pig: 100%; Rabbit: 100%; Rat: 93%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
45kDa
Shipping Conditions
Wet Ice
Protein Length
463
NCBI Gene Symbol
SUCLA2
NCBI GB Accession Number
SUCLA2
Host or Source
Rabbit
Protein Name
Succinyl-CoA ligase [ADP-forming] subunit beta, mitochondrial
Nucleotide Accession Number
NM_003850
Peptide Sequence
FDLQDWTQEDERDKDAAKANLNYIGLDGNIGCLVNGAGLAMATMDIIKLH
Subunit
Beta, mitochondrial
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