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LTBP4 Antibody - C-terminal region: FITC (ARP64662_P050-FITC)

Product Specifications

Gene Name

Latent transforming growth factor beta binding protein 4

Gene Aliases

ARCL1C, LTBP-4, LTBP4L, LTBP4S

Gene ID

8425

Swiss Prot

Q8N2S1-4

Host

Rabbit

Reactivity

Human, Cow, Dog, Horse, Rabbit

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human LTBP4

Target

The protein encoded by this gene binds transforming growth factor beta (TGFB) as it is secreted and targeted to the extracellular matrix. TGFB is biologically latent after secretion and insertion into the extracellular matrix, and sheds TGFB and other proteins upon activation. Defects in this gene may be a cause of cutis laxa and severe pulmonary, gastrointestinal, and urinary abnormalities. Three transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

FBXO6; HCVgp1; FRAT1; UBC; RAC1; FBLN1; CRY1; GFI1B; ATN1; ITSN2; CRKL; ATXN7; CACNA1A; TGFB1; TRIB3

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 93%; Dog: 86%; Horse: 86%; Human: 100%; Rabbit: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

69kDa

Shipping Conditions

Wet Ice

Protein Length

636

NCBI Gene Symbol

LTBP4

Protein Name

Latent-transforming growth factor beta-binding protein 4

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