PDE8B Antibody - middle region : Biotin (ARP64625_P050-Biotin)
Selected Variant
ARP64625_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Phosphodiesterase 8B
Gene Aliases
ADSD, PPNAD3
Gene ID
8622
Swiss Prot
O95263-2
Accession Number
NP_001025022
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Zebrafish
Target
The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD) . Several transcript variants encoding different isoforms have been found for this gene.
Partner Proteins
UBC
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Zebrafish: 79%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
87kDa
Shipping Conditions
Wet Ice
Protein Length
788
NCBI Gene Symbol
PDE8B
NCBI GB Accession Number
PDE8B
Host or Source
Rabbit
Protein Name
High affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B
Nucleotide Accession Number
NM_001029851
Peptide Sequence
TELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGNEYVFTKNVHQSHSHL
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