ITGAV Antibody - C-terminal region : FITC (ARP64575_P050-FITC)

ITAGV encodes integrin alpha chain V. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. The I-domain containing integrin alpha V undergoes post-translational cleavage to yield disulfide-linked heavy and light chains, that combine with multiple integrin beta chains to form different integrins. Among the known associating beta chains (beta chains 1,3,5,6, and 8; 'ITGB1', 'ITGB3', 'ITGB5', 'ITGB6', and 'ITGB8'), each can interact with extracellular matrix ligands; the alpha V beta 3 integrin, perhaps the most studied of these, is referred to as the Vitronectin receptor (VNR) . In addition to adhesion, many integrins are known to facilitate signal transduction. Alternative splicing results in multiple transcript variants.

UBC; EPHA2; THBS1; FN1; KRT3; MCAT; FBXO6; BCAR1; PXN; PHKA2; CSF1R; CBL; MMP2; ILK; PLP1; CALR; ANGPTL3; EDIL3; CYR61; PAK4; ITGB8; ADAM9; AUP1; CD47; PTK2; MMP14; P2RY2; L1CAM; AZGP1; TGFB1; THY1; F2R; PDGFRA; ITGB3; SPP1; ITGB5; ITGB6; ITGB1; NID1; ICA

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.