CYFIP1 Antibody - C-terminal region : Biotin (ARP64537_P050-Biotin)

CYFIP1 is a component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. CYFIP1 promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA By similarity. CYFIP1 regulates formation of membrane ruffles and lamellipodia. CYFIP1 plays a role in axon outgrowth. CYFIP1 binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. CYFIP1 may act as an invasion suppressor in cancers.

EFHC2; SUMO2; MEOX1; UBC; WWOX; PRPF40A; CLUH; TCERG1; NCKAP1; ARHGEF1; GAS7; APBB1; HECW2; RFX6; EFTUD2; SCTR; PPP1CC; GNB1; UBD; MARK4; YWHAZ; YWHAH; RYK; TERF2; TERF1; CYFIP1; RAC1; FMR1; ACTA1; FXR2; FXR1; NCL

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.