AQR Antibody - C-terminal region : Biotin (ARP64428_P050-Biotin)
Product Specifications
Gene Name
Aquarius homolog (mouse)
Gene Aliases
IBP160, fSAP164
Gene ID
9716
Swiss Prot
O60306
Accession Number
NP_055506
Host
Rabbit
Reactivity
Human, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human AQR
Target
AQR is an intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis. AQR plays a key role in position-dependent assembly of intron-encoded box C/D small snoRNP, splicing being required for snoRNP assembly. AQR may act by helping the folding of the snoRNA sequence. Binds to intron of pre-mRNAs in a sequence-independent manner, contacting the region between snoRNA and the branchpoint of introns (40 nucleotides upstream of the branchpoint) during the late stages of splicing.
Partner Proteins
UBC; LGR4; SUZ12; RNF2; BMI1; ZNF830; WDR83; WDR77; RBM22; PQBP1; RBM4; EIF4A3; MAGOH; SIRT7; HNRNPA1; Prpf8; Cdc5l; Snw1; USP28
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
AQR is supported by BioGPS gene expression data to be expressed in MCF7
Concentration
0.5 mg/ml
Homology
Horse: 79%; Human: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
171kDa
Shipping Conditions
Wet Ice
Protein Length
1485
NCBI Gene Symbol
AQR
NCBI GB Accession Number
AQR
Host or Source
Rabbit
Protein Name
Intron-binding protein aquarius
Nucleotide Accession Number
NM_014691
Peptide Sequence
DTTPSETGATSTPEAIPALSETTPTVVGAVSAPAEANTPQDATSAPEETK
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