DGUOK Antibody - C-terminal region: FITC (ARP64409_P050-FITC)
Product Specifications
Gene Aliases
DGK, NCPH, PEOB4, MTDPS3
Gene ID
1716
Swiss Prot
Q16854
Accession Number
NP_550438
Host
Rabbit
Reactivity
Human, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human DGUOK
Target
In mammalian cells, the phosphorylation of purine deoxyribonucleosides is mediated predominantly by two deoxyribonucleoside kinases, cytosolic deoxycytidine kinase and mitochondrial deoxyguanosine kinase. The protein encoded by this gene is responsible for phosphorylation of purine deoxyribonucleosides in the mitochondrial matrix. In addition, this protein phosphorylates several purine deoxyribonucleoside analogs used in the treatment of lymphoproliferative disorders, and this phosphorylation is critical for the effectiveness of the analogs. Alternative splice variants encoding different protein isoforms have been described for this gene.
Partner Proteins
UBC; PXN; LIG4; APP; DGUOK
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Sample Type
DGUOK is strongly supported by BioGPS gene expression data to be expressed in 721_B
Concentration
0.5 mg/mL
Homology
Cow: 86%; Dog: 93%; Guinea Pig: 79%; Horse: 79%; Human: 100%; Pig: 86%; Rabbit: 86%; Rat: 85%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
28kDa
Shipping Conditions
Wet Ice
Protein Length
277
NCBI Gene Symbol
DGUOK
Protein Name
Deoxyguanosine kinase, mitochondrial
Nucleotide Accession Number
NM_080916
Curated Selection
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