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CDC14A Antibody - C-terminal region : FITC (ARP64325_P050-FITC)

Selected Variant

ARP64325_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

CDC14 cell division cycle 14 homolog A (S. cerevisiae)

Gene Aliases

Cdc14, DFNB32, DFNB35, hCDC14, DFNB105

Gene ID

8556

Swiss Prot

Q9UNH5

Accession Number

NP_003663

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Target

The protein encoded by this gene is a member of the dual specificity protein tyrosine phosphatase family. It is highly similar to Saccharomyces cerevisiae Cdc14, a protein tyrosine phosphatase involved in the exit of cell mitosis and initiation of DNA replication, suggesting a role in cell cycle control. This protein has been shown to interact with, and dephosphorylate tumor suppressor protein p53, and is thought to regulate the function of p53. Alternative splicing of this gene results in several transcript variants encoding distinct isoforms.

Partner Proteins

CHRM1; CDC6; CDC25B; POLR2A; NPM1; FZR1; TP53; CCNB1; KIF20A; BRAP

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

CDC14A is strongly supported by BioGPS gene expression data to be expressed in RPMI-8226

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 87%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 93%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

66kDa

Shipping Conditions

Wet Ice

Protein Length

594

NCBI Gene Symbol

CDC14A

NCBI GB Accession Number

CDC14A

Host or Source

Rabbit

Protein Name

Dual specificity protein phosphatase CDC14A

Nucleotide Accession Number

NM_003672

Peptide Sequence

DDDVEMKNGITQGDKLRALKSQRQPRTSPSCAFRSDDTKGHPRAVSQPFR

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