BANF1 Antibody - middle region : Biotin (ARP64252_P050-Biotin)

The protein encoded by this gene was first identified by its ability to protect retroviruses from intramolecular integration and therefore promote intermolecular integration into the host cell genome. The protein forms a homodimer which localizes to both the nucleus and cytoplasm and is specifically associated with chromosomes during mitosis. This protein binds to double stranded DNA in a non-specific manner and also binds to LEM-domain containing proteins of the nuclear envelope. This protein is thought to facilitate nuclear reassembly by binding with both DNA and inner nuclear membrane proteins and thereby recruit chromatin to the nuclear periphery. Alternative splicing results in multiple transcript variants encoding the same protein.

UBC; ERBB2IP; HIST1H3B; EMD; FBL; CRX; ATP6V1B1; LUC7L3; TMPO; EHMT2; SET; EVC2; ZNF428; LMNB2; DPY30; SMOC2; APTX; ACIN1; CBX3; PSIP1; CBX1; SUB1; CD2BP2; MDC1; BCL7C; MTA2; BANF1; CUL4A; CHAF1B; XPC; TUFM; SNRPD3; SMARCE1; SMARCC2; SMARCA2; TRA2B; DPF2

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.