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CDK2AP1 Antibody - C-terminal region : HRP (ARP64230_P050-HRP)

Selected Variant

ARP64230_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Cyclin-dependent kinase 2 associated protein 1

Gene Aliases

DOC1, ST19, DORC1, doc-1, p12DOC-1

Gene ID

8099

Swiss Prot

O14519

Accession Number

NP_004633

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human CDK2AP1

Target

The protein encoded by this gene is a specific CDK2-associated protein, which is thought to negatively regulate CDK2 activity by sequestering monomeric CDK2, and targeting CDK2 for proteolysis. This protein was found to also interact with DNA polymerase alpha/primase and mediate the phosphorylation of the large p180 subunit, which suggested the regulatory role in DNA replication during S phase of the cell cycle. A similar gene in hamster was isolated from, and functions as a growth suppressor of normal keratinocytes.

Partner Proteins

MRFAP1L1; CCDC136; HDAC2; HDAC1; ZNF420; MTA3; VCP; CDK2AP2; Cebpb; HHV8GK18_gp81; ELAVL1; MBD3; MBD2; RBBP7; RBBP4; SRRM2; POLA1; CDK2; IGHA2; IGHA1; AMY1A

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

12kDa

Shipping Conditions

Wet Ice

Protein Length

115

NCBI Gene Symbol

CDK2AP1

NCBI GB Accession Number

CDK2AP1

Host or Source

Rabbit

Protein Name

Cyclin-dependent kinase 2-associated protein 1

Nucleotide Accession Number

NM_004642

Peptide Sequence

LLAIIEELGKEIRPTYAGSKSAMERLKRGIIHARGLVRECLAETERNARS

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