UNC13D Antibody - C-terminal region : Biotin (ARP64215_P050-Biotin)
Selected Variant
ARP64215_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Unc-13 homolog D (C. elegans)
Gene Aliases
FHL3, HLH3, HPLH3, Munc13-4
Gene ID
201294
Swiss Prot
Q70J99
Accession Number
NP_954712
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of Human UNC13D
Target
This gene encodes a protein that is a member of the UNC13 family, containing similar domain structure as other family members but lacking an N-terminal phorbol ester-binding C1 domain present in other Munc13 proteins. The protein appears to play a role in vesicle maturation during exocytosis and is involved in regulation of cytolytic granules secretion. Mutations in this gene are associated with familial hemophagocytic lymphohistiocytosis type 3, a genetically heterogeneous, rare autosomal recessive disorder.
Partner Proteins
UBC; CUL5; VPS37B; XRN2; LMNA; RAB27B; RAB27A
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 92%; Dog: 93%; Guinea Pig: 92%; Horse: 93%; Human: 100%; Mouse: 92%; Rabbit: 86%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
119kDa
Shipping Conditions
Wet Ice
Protein Length
1090
NCBI Gene Symbol
UNC13D
NCBI GB Accession Number
UNC13D
Host or Source
Rabbit
Protein Name
Protein unc-13 homolog D
Nucleotide Accession Number
NM_199242
Peptide Sequence
SGSEEPGEVPQTRLPLTYPAPNGDPILQLLEGRKGDREAQVFVRLRRHRA
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