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SEC62 Antibody - middle region: FITC (ARP64182_P050-FITC)

Product Specifications

Gene Name

SEC62 homolog (S. cerevisiae)

Gene Aliases

HTP1, TP-1, Dtrp1, TLOC1

Gene ID

7095

Swiss Prot

Q99442

Accession Number

NP_003253

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Target

The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.

Partner Proteins

UBC; ZNF24; SEC62; env; GLUD1; CIC; SEC63

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

SEC62 is strongly supported by BioGPS gene expression data to be expressed in NCI-H226

Concentration

0.5 mg/mL

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 86%; Rabbit: 93%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

46kDa

Shipping Conditions

Wet Ice

Protein Length

399

NCBI Gene Symbol

SEC62

Protein Name

Translocation protein SEC62

Nucleotide Accession Number

NM_003262

Curated Selection

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