GPBAR1 Antibody - C-terminal region: FITC (ARP64154_P050-FITC)
Product Specifications
Gene Name
G protein-coupled bile acid receptor 1
Gene Aliases
BG37, TGR5, M-BAR, GPCR19, GPR131
Gene ID
151306
Swiss Prot
Q8TDU6
Accession Number
NP_733800
Host
Rabbit
Reactivity
Human, Rat
Target
This gene encodes a member of the G protein-coupled receptor (GPCR) superfamily. This enzyme functions as a cell surface receptor for bile acids. Treatment of cells expressing this GPCR with bile acids induces the production of intracellular cAMP, activation of a MAP kinase signaling pathway, and internalization of the receptor. The receptor is implicated in the suppression of macrophage functions and regulation of energy homeostasis by bile acids.
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Human: 100%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
35kDa
Shipping Conditions
Wet Ice
Protein Length
330
NCBI Gene Symbol
GPBAR1
Protein Name
G-protein coupled bile acid receptor 1
Nucleotide Accession Number
NM_170699
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