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SMC6 Antibody - C-terminal region : Biotin (ARP64076_P050-Biotin)

Product Specifications

Gene Name

Structural maintenance of chromosomes 6

Gene Aliases

SMC-6, hSMC6, SMC6L1

Gene ID

79677

Swiss Prot

Q96SB8

Accession Number

NP_078900

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human SMC6

Target

SMC6 is a core component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination. The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks.

Partner Proteins

UBC; NSMCE1; NSMCE2; SMC6; NDNL2; NSMCE4A; SMC5; SUMO1; EID3; ALK

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

SMC6 is supported by BioGPS gene expression data to be expressed in MCF7

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

126kDa

Shipping Conditions

Wet Ice

Protein Length

1091

NCBI Gene Symbol

SMC6

NCBI GB Accession Number

SMC6

Host or Source

Rabbit

Protein Name

Structural maintenance of chromosomes protein 6

Nucleotide Accession Number

NM_024624

Peptide Sequence

MADSQRFRQFILLTPQSMSSLPSSKLIRILRMSDPERGQTTLPFRPVTQE

Frequently Asked Questions

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