PDE11A Antibody - C-terminal region : HRP (ARP64064_P050-HRP)
Product Specifications
Gene Name
Phosphodiesterase 11A
Gene Aliases
PPNAD2
Gene ID
50940
Swiss Prot
Q9HCR9-4
Accession Number
NP_001070664
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish
Target
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia.
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 91%; Zebrafish: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
56kDa
Shipping Conditions
Wet Ice
Product Datasheet
Anti-PDE11A (ARP64064_P050-HRP) antibody
Protein Length
489
NCBI Gene Symbol
PDE11A
NCBI GB Accession Number
PDE11A
Host or Source
Rabbit
Protein Name
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
Nucleotide Accession Number
NM_001077196
Peptide Sequence
VTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQA
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