PDE11A Antibody - C-terminal region : Biotin (ARP64064_P050-Biotin)
Selected Variant
ARP64064_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Phosphodiesterase 11A
Gene Aliases
PPNAD2
Gene ID
50940
Swiss Prot
Q9HCR9-4
Accession Number
NP_001070664
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish
Target
The 3',5'-cyclic nucleotides cAMP and cGMP function as second messengers in a wide variety of signal transduction pathways. 3',5'-cyclic nucleotide phosphodiesterases (PDEs) catalyze the hydrolysis of cAMP and cGMP to the corresponding 5'-monophosphates and provide a mechanism to downregulate cAMP and cGMP signaling. This gene encodes a member of the PDE protein superfamily. Mutations in this gene are a cause of Cushing disease and adrenocortical hyperplasia.
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 91%; Zebrafish: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
56kDa
Shipping Conditions
Wet Ice
Protein Length
489
NCBI Gene Symbol
PDE11A
NCBI GB Accession Number
PDE11A
Host or Source
Rabbit
Protein Name
Dual 3',5'-cyclic-AMP and -GMP phosphodiesterase 11A
Nucleotide Accession Number
NM_001077196
Peptide Sequence
VTSEFFEQGDRERLELKLTPSAIFDRNRKDELPRLQLEWIDSICMPLYQA
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