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RAP2A Antibody - C-terminal region : FITC (ARP64032_P050-FITC)

Selected Variant

ARP64032_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

RAP2A, member of RAS oncogene family

Gene Aliases

KREV, RAP2, K-REV, RbBP-30

Gene ID

5911

Swiss Prot

P10114

Accession Number

NP_066361

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Target

RAP2A is a small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. In its active form interacts with and regulates several effectors including MAP4K4, MINK1 and TNIK. Part of a signaling complex composed of NEDD4, RAP2A and TNIK which regulates neuronal dendrite extension and arborization during development. More generally, it is part of several signaling cascades and may regulate cytoskeletal rearrangements, cell migration, cell adhesion and cell spreading.

Partner Proteins

UBC; RPTOR; ELAVL1; RRP9; TM7SF2; PLG; SERPINA1; FTL; FKBP2; ENSA; EEF1A1; NEDD4; TNIK; RUNDC3A; GRIN1; RASIP1; RAPGEF5; RAPGEF6; ARHGAP29; RASSF5; MAP4K4; BMPR1B; GRIN2D; RGS14; RALGDS; SMAD1; TGFBR1; RAP2A; RAF1; MLLT4; FNTB; ACVR1; RAPGEF4; RAPGEF3; RA

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Rabbit: 86%; Rat: 93%; Sheep: 93%; Zebrafish: 79%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

20kDa

Shipping Conditions

Wet Ice

Protein Length

183

NCBI Gene Symbol

RAP2A

NCBI GB Accession Number

RAP2A

Host or Source

Rabbit

Protein Name

Ras-related protein Rap-2a

Nucleotide Accession Number

NM_021033

Peptide Sequence

QIIRVKRYEKVPVILVGNKVDLESEREVSSSEGRALAEEWGCPFMETSAK

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