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LIMS1 Antibody - C-terminal region : FITC (ARP64006_P050-FITC)

Selected Variant

ARP64006_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

LIM and senescent cell antigen-like domains 1

Gene Aliases

PINCH, PINCH1, PINCH-1

Gene ID

3987

Swiss Prot

B7Z7R3

Accession Number

NP_001180414

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

Target

The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.

Partner Proteins

RSU1; UBC; SUMO1; NEDD8; ILK; STUB1; MAPT; MBIP; Hoxa1; HNRNPU; STK11; PARVA; SMURF1; EHMT2; LPXN; NCK2; RBBP8; TMSB4X; TGFBR1; ACP6

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

44kDa

Shipping Conditions

Wet Ice

Protein Length

387

NCBI Gene Symbol

LIMS1

NCBI GB Accession Number

LIMS1

Host or Source

Rabbit

Protein Name

LIM and senescent cell antigen-like-containing domain protein 1

Nucleotide Accession Number

NM_001193485

Peptide Sequence

VNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKFPLELKKRLKKLAETL

Price

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