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WASF1 Antibody : FITC (ARP63994_P050-FITC)

Selected Variant

ARP63994_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

WAS protein family, member 1

Gene Aliases

WAVE, SCAR1, WAVE1, NEDALVS

Gene ID

8936

Swiss Prot

Q92558

Accession Number

NP_003922

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

Immunogen

The immunogen is a synthetic peptide directed towards the following sequence TPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRP

Target

The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP) -family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.

Partner Proteins

IFT20; TRIP10; PRKAR2A; PRKACA; ABL1; ZC3H15; TXNDC9; SORBS2; PTPN12; UBC; RYK; BRK1; SRGAP3; DNMBP; CYFIP2; PSTPIP1; NCKAP1; ACTR2; BAD; ABI1; RAC1; NCK1; NCF1; PFN1; CRK; IL12A; CXCL8; GNAI1; FYN; CDK5; CDC42; GRB2; ACTB; ACTG1; ARPC3; BAIAP2; ARHGEF2

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 83%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

62 kDa

Shipping Conditions

Wet Ice

Protein Length

559

NCBI Gene Symbol

WASF1

NCBI GB Accession Number

WASF1

Host or Source

Rabbit

Protein Name

Wiskott-Aldrich syndrome protein family member 1

Nucleotide Accession Number

NM_001024934

Peptide Sequence

TPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRP

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