WASF1 Antibody: FITC (ARP63994_P050-FITC)
Product Specifications
Gene Name
WAS protein family, member 1
Gene Aliases
WAVE, SCAR1, WAVE1, NEDALVS
Gene ID
8936
Swiss Prot
Q92558
Accession Number
NP_003922
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the following sequence TPYRDDGKEGLKFYTNPSYFFDLWKEKMLQDTEDKRKEKRKQKQKNLDRP
Target
The protein encoded by this gene, a member of the Wiskott-Aldrich syndrome protein (WASP) -family, plays a critical role downstream of Rac, a Rho-family small GTPase, in regulating the actin cytoskeleton required for membrane ruffling. It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro. Wiskott-Aldrich syndrome is a disease of the immune system, likely due to defects in regulation of actin cytoskeleton. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Partner Proteins
IFT20; TRIP10; PRKAR2A; PRKACA; ABL1; ZC3H15; TXNDC9; SORBS2; PTPN12; UBC; RYK; BRK1; SRGAP3; DNMBP; CYFIP2; PSTPIP1; NCKAP1; ACTR2; BAD; ABI1; RAC1; NCK1; NCF1; PFN1; CRK; IL12A; CXCL8; GNAI1; FYN; CDK5; CDC42; GRB2; ACTB; ACTG1; ARPC3; BAIAP2; ARHGEF2
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IHC
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 83%; Zebrafish: 92%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
62 kDa
Shipping Conditions
Wet Ice
Protein Length
559
NCBI Gene Symbol
WASF1
Protein Name
Wiskott-Aldrich syndrome protein family member 1
Nucleotide Accession Number
NM_001024934
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