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ITGA2B Antibody - N-terminal region : Biotin (ARP63955_P050-Biotin)

Selected Variant

ARP63955_P050-Biotin

Size: 100 µL

Product Specifications

Gene Name

Integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41)

Gene Aliases

GT, GTA, CD41, GP2B, HPA3, CD41B, GPIIb, BDPLT2, BDPLT16, PPP1R93

Gene ID

3674

Swiss Prot

P08514

Accession Number

NP_000410

Host

Rabbit

Reactivity

Human, Mouse, Rat, Dog, Guinea Pig, Horse, Pig, Rabbit, Yeast

Target

ITGA2B encodes integrin alpha chain 2b. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. Alpha chain 2b undergoes post-translational cleavage to yield disulfide-linked light and heavy chains that join with beta 3 to form a fibronectin receptor expressed in platelets that plays a crucial role in coagulation. Mutations that interfere with this role result in thrombasthenia. In addition to adhesion, integrins are known to participate in cell-surface mediated signalling.

Partner Proteins

FBXO6; PRKACA; CAMK2A; ITGA2B; AUP1; CIB1; CLNS1A; VWF; TLN1; F2; CD36; ITGB3; FGA; COL1A2; COL2A1; CALR; GRB2; RNF181

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Dog: 100%; Guinea Pig: 86%; Horse: 92%; Human: 100%; Mouse: 85%; Pig: 92%; Rabbit: 85%; Rat: 92%; Yeast: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

16kDa

Shipping Conditions

Wet Ice

Protein Length

1039

NCBI Gene Symbol

ITGA2B

NCBI GB Accession Number

ITGA2B

Host or Source

Rabbit

Protein Name

Integrin alpha-IIb

Nucleotide Accession Number

NM_000419

Peptide Sequence

QGLGASVVSWSDVIVACAPWQHWNVLEKTEEAEKTPVGSCFLAQPESGRR

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