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PMM2 Antibody - N-terminal region: Biotin (ARP63939_P050-Biotin)

Product Specifications

Gene Name

Phosphomannomutase 2

Gene Aliases

PMI, CDG1, CDGS, PMI1, CDG1a, PMM 2

Gene ID

5373

Swiss Prot

O15305

Accession Number

NP_000294

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

Target

The protein encoded by this gene catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate, which is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. Mutations in this gene have been shown to cause defects in glycoprotein biosynthesis, which manifests as carbohydrate-deficient glycoprotein syndrome type I.

Partner Proteins

ACY3; SUMO2; UBC; TAGLN3

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 93%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

28kDa

Shipping Conditions

Wet Ice

Protein Length

246

NCBI Gene Symbol

PMM2

Protein Name

Phosphomannomutase 2

Nucleotide Accession Number

NM_000303

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