Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

AP219

AP39 (Item No. 17100) is a compound used to increase the levels of hydrogen sulfide (H2S) within mitochondria. It consists of a mitochondria-targeting motif (triphenylphosphonium) coupled to an H2S-donating moiety (dithiolethione) by an aliphatic linker. AP219 is a control compound for AP39, containing the triphenylphosphonium scaffold but lacking the H2S-releasing portion.

Product Specifications

CAS Number

779282-36-9

UNSPSC

12352005

Hazard Statement

H302-H315-H319-H335

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/ap219.html

Smiles

OC(CCCCCCCCC[P+](C1=CC=CC=C1)(C2=CC=CC=C2)C3=CC=CC=C3)=O

Molecular Formula

C28H34O2P+

Molecular Weight

433.54

Precautions

P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

References & Citations

[1]Szczesny, et al. AP39, a novel mitochondria-targeted hydrogen sulfide donor, stimulates cellular bioenergetics, exerts cytoprotective effects and protects against the loss of mitochondrial DNA integrity in oxidatively stressed endothelial cells in vitro. Nitric Oxide 41, 120-130 (2014) .

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

More Discoveries

Explore Other Products

Browse additional items from our catalog

Polyclonal Bola2 antibody - N-terminal region
APR00714G 0.05mg

Polyclonal Bola2 antibody - N-terminal region

Sign In for Pricing
View Details
LentimiRa-hsa-mir-548x Vector
mh40856 500 ng

LentimiRa-hsa-mir-548x Vector

Sign In for Pricing
View Details
TRXRD2/SELZ Polyclonal Antibody, APC-Cy5.5 Conjugated
bs-8628R-APC-Cy5.5 100 µL

TRXRD2/SELZ Polyclonal Antibody, APC-Cy5.5 Conjugated

Sign In for Pricing
View Details
LB Broth Top Agar
SD7004 250g

LB Broth Top Agar

Sign In for Pricing
View Details
Olfr1270 CRISPR Activation Plasmid (m2)
sc-435069-ACT-2 20 µg

Olfr1270 CRISPR Activation Plasmid (m2)

Sign In for Pricing
View Details
NXT2 Rabbit Polyclonal Antibody (BF594)
orb2417668 100 µL

NXT2 Rabbit Polyclonal Antibody (BF594)

Sign In for Pricing
View Details