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HSPA1B Antibody - C-terminal region : HRP (ARP63869_P050-HRP)

Selected Variant

ARP63869_P050-HRP

Size: 100 µL

Product Specifications

Gene Name

Heat shock 70kDa protein 1B

Gene Aliases

HSP72, HSPA1, HSX70, HSP70-1, HSP70-2, HSP70.1, HSP70.2, HSP70-1B

Gene ID

3304

Swiss Prot

P08107

Accession Number

NP_005337

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Target

This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins.

Partner Proteins

PA2G4; STUB1; UBC; TP53; BAG4; STAU1; TRIM25; RNF2; EZH2; FBXO6; PINK1; UBD; ADRB2; UBL4A; VCAM1; TGM2; PPP5C; ITGA4; HSP90AA1; FN1; DAB2; SMURF1; CTNNB1; FMNL1; UBASH3B; SHC1; PIK3R2; INPPL1; GRB2; EPS15; CRK; AP2M1; CBL; HSPBP1; CAND1; DCUN1D1; COPS5; C

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Sample Type

HSPA1B is strongly supported by BioGPS gene expression data to be expressed in MDA-MB435

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 93%; Goat: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 86%; Rabbit: 100%; Rat: 93%; Sheep: 100%; Zebrafish: 93%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

70kDa

Shipping Conditions

Wet Ice

Protein Length

641

NCBI Gene Symbol

HSPA1B

NCBI GB Accession Number

HSPA1B

Host or Source

Rabbit

Protein Name

Heat shock 70 kDa protein 1A/1B

Nucleotide Accession Number

NM_005346

Peptide Sequence

DKSTGKANKITITNDKGRLSKEEIERMVQEAEKYKAEDEVQRERVSAKNA

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