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MCPH1 Antibody - C-terminal region: Biotin (ARP63864_P050-Biotin)

Product Specifications

Gene Name

Microcephalin 1

Gene Aliases

MCT, BRIT1

Gene ID

79648

Swiss Prot

E9PH63

Host

Rabbit

Reactivity

Human

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human MCPH1

Target

This gene encodes a DNA damage response protein. The encoded protein may play a role in G2/M checkpoint arrest via maintenance of inhibitory phosphorylation of cyclin-dependent kinase 1. Mutations in this gene have been associated with primary autosomal recessive microcephaly 1 and premature chromosome condensation syndrome.

Partner Proteins

KDM1A; PHF11; TADA2A; ABCC2; E2F1; CDC27; CHD4; H2AFX; CHEK1; MDC1; TP53BP1; SMARCC2; SMARCC1; SMARCB1; SMARCA4; SMARCA2; RAD51; NBN; MCM2; BRCA2; ATR; ATM; RPA1

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Human: 100%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

61kDa

Shipping Conditions

Wet Ice

Protein Length

562

NCBI Gene Symbol

MCPH1

Protein Name

Microcephalin Ensembl ENSP00000430768

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