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CDC73 Antibody - C-terminal region: HRP (ARP63639_P050-HRP)

Product Specifications

Gene Name

Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)

Gene Aliases

HYX, FIHP, HPTJT, HRPT1, HRPT2, C1orf28

Gene ID

79577

Swiss Prot

Q6P1J9

Accession Number

NP_078805

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Zebrafish

Target

This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma

Partner Proteins

CCDC155; FSD2; TSGA10; CEP70; VPS37B; MTUS2; UBC; TFCP2; GOLGA2; ALAS1; CIAO1; AURKB; GPRASP2; COG3; MYH14; MYL12A; ARFGEF2; NUP98; MYH9; CHUK; DNMT3B; DNMT3A; SOX2; BCL9L; PAF1; CTR9; TCF4; CTNNB1; LEO1; GTF2F1; SUV39H1; PTPN11; WDR61; HIST1H3A; RNF20; R

Clonality

Polyclonal

Conjugation

HRP: Horseradish Peroxidase

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/mL

Homology

Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 77%

Format

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

58kDa

Shipping Conditions

Wet Ice

Protein Length

531

NCBI Gene Symbol

CDC73

Protein Name

Parafibromin

Nucleotide Accession Number

NM_024529

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