CDC73 Antibody - C-terminal region: HRP (ARP63639_P050-HRP)
Product Specifications
Gene Name
Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae)
Gene Aliases
HYX, FIHP, HPTJT, HRPT1, HRPT2, C1orf28
Gene ID
79577
Swiss Prot
Q6P1J9
Accession Number
NP_078805
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Horse, Rabbit, Zebrafish
Target
This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma
Partner Proteins
CCDC155; FSD2; TSGA10; CEP70; VPS37B; MTUS2; UBC; TFCP2; GOLGA2; ALAS1; CIAO1; AURKB; GPRASP2; COG3; MYH14; MYL12A; ARFGEF2; NUP98; MYH9; CHUK; DNMT3B; DNMT3A; SOX2; BCL9L; PAF1; CTR9; TCF4; CTNNB1; LEO1; GTF2F1; SUV39H1; PTPN11; WDR61; HIST1H3A; RNF20; R
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 77%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
58kDa
Shipping Conditions
Wet Ice
Protein Length
531
NCBI Gene Symbol
CDC73
Protein Name
Parafibromin
Nucleotide Accession Number
NM_024529
Curated Selection
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