IDUA Antibody - middle region : Biotin (ARP63636_P050-Biotin)
Selected Variant
ARP63636_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Iduronidase, alpha-L-
Gene Aliases
IDA, MPS1, MPSI
Gene ID
3425
Swiss Prot
P35475
Accession Number
NP_000194.2
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the middle region of mouse IDUA
Target
This gene encodes an enzyme that hydrolyzes the terminal alpha-L-iduronic acid residues of two glycosaminoglycans, dermatan sulfate and heparan sulfate. This hydrolysis is required for the lysosomal degradation of these glycosaminoglycans. Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I) .
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 86%; Dog: 90%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 86%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
30kDa
Shipping Conditions
Wet Ice
Protein Length
281
NCBI Gene Symbol
IDUA
NCBI GB Accession Number
IDUA
Host or Source
Rabbit
Protein Name
Alpha-L-iduronidase
Nucleotide Accession Number
NM_000203.4
Peptide Sequence
MENQLLPGFELMGSPSGYFTDFDDKQQVFEWKDLVSLLARRYIGRYGLTH
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