TCP1 Antibody - C-terminal region : Biotin (ARP63619_P050-Biotin)

Product Specifications

Gene Name

T-complex 1

Gene Aliases

CCT1, CCTa, D6S230E, CCT-alpha, TCP-1-alpha

Gene ID

6950

Swiss Prot

P17987

Accession Number

NP_110379

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

Target

The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found.

Partner Proteins

FUS; ERLIN2; HUWE1; CBFA2T2; UBC; TP53; NEDD1; VHL; TUBG1; SUMO2; LGALS3BP; CDC20; STAU1; INPP5K; CDC5L; VRK2; PPP4C; COPA; COPG1; USP9X; PARK2; FBXO6; YWHAQ; UBD; FBXW4; FBXO46; STK25; HDAC6; HDAC3; NPM1; ILK; CDK5; CDK2; PAN2; US3; FAM86B2; CFAP52; METT

Clonality

Polyclonal

Conjugation

Biotin

Type

Polyclonal Antibody

Applications

Purification

Affinity Purified

Sample Type

TCP1 is strongly supported by BioGPS gene expression data to be expressed in HeLa

Concentration

0.5 mg/ml

Homology

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.