PDIA3 Antibody - C-terminal region: FITC (ARP63565_P050-FITC)
Product Specifications
Gene Name
Protein disulfide isomerase family A, member 3
Gene Aliases
P58, ER60, ERp57, ERp60, ERp61, GRP57, GRP58, PI-PLC, HsT17083, HEL-S-269, HEL-S-93n
Gene ID
2923
Swiss Prot
P30101
Accession Number
NP_005304
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish
Target
This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.
Partner Proteins
FUS; UBC; MDM2; SUZ12; ABCE1; RBBP4; RAB1A; PGD; MTAP; MTPN; BCCIP; CNDP2; NANS; DAK; ACOT7; NPEPPS; SLC9A3R1; RPL23; SMS; LDHA; HSPD1; CSE1L; ATP6V1A; ADSS; EGFR; UBD; CANX; CALR; HDAC10; MTOR; EFEMP1; ATF2; COL6A1; CLU; APP; ADAM10; AGRN; DCBLD1; RICTOR
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
IHC, IP, WB
Purification
Affinity Purified
Sample Type
PDIA3 is supported by BioGPS gene expression data to be expressed in 721_B
Concentration
0.5 mg/mL
Homology
Cow: 93%; Dog: 100%; Goat: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 93%; Rat: 100%; Sheep: 93%; Zebrafish: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
56kDa
Shipping Conditions
Wet Ice
Protein Length
505
NCBI Gene Symbol
PDIA3
Protein Name
Protein disulfide-isomerase A3
Nucleotide Accession Number
NM_005313
Curated Selection
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