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PDIA3 Antibody - C-terminal region : FITC (ARP63565_P050-FITC)

Selected Variant

ARP63565_P050-FITC

Size: 100 µL

Product Specifications

Gene Name

Protein disulfide isomerase family A, member 3

Gene Aliases

P58, ER60, ERp57, ERp60, ERp61, GRP57, GRP58, PI-PLC, HsT17083, HEL-S-269, HEL-S-93n

Gene ID

2923

Swiss Prot

P30101

Accession Number

NP_005304

Host

Rabbit

Reactivity

Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

Target

This gene encodes a protein of the endoplasmic reticulum that interacts with lectin chaperones calreticulin and calnexin to modulate folding of newly synthesized glycoproteins. The protein was once thought to be a phospholipase; however, it has been demonstrated that the protein actually has protein disulfide isomerase activity. It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates.

Partner Proteins

FUS; UBC; MDM2; SUZ12; ABCE1; RBBP4; RAB1A; PGD; MTAP; MTPN; BCCIP; CNDP2; NANS; DAK; ACOT7; NPEPPS; SLC9A3R1; RPL23; SMS; LDHA; HSPD1; CSE1L; ATP6V1A; ADSS; EGFR; UBD; CANX; CALR; HDAC10; MTOR; EFEMP1; ATF2; COL6A1; CLU; APP; ADAM10; AGRN; DCBLD1; RICTOR

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

IHC, IP, WB

Purification

Affinity Purified

Sample Type

PDIA3 is supported by BioGPS gene expression data to be expressed in 721_B

Concentration

0.5 mg/ml

Homology

Cow: 93%; Dog: 100%; Goat: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 92%; Rabbit: 93%; Rat: 100%; Sheep: 93%; Zebrafish: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

56kDa

Shipping Conditions

Wet Ice

Protein Length

505

NCBI Gene Symbol

PDIA3

NCBI GB Accession Number

PDIA3

Host or Source

Rabbit

Protein Name

Protein disulfide-isomerase A3

Nucleotide Accession Number

NM_005313

Peptide Sequence

YFSPANKKLNPKKYEGGRELSDFISYLQREATNPPVIQEEKPKKKKKAQE

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