SOST Antibody : FITC (ARP63543_P050-FITC)
Product Specifications
Gene Name
Sclerostin
Gene Aliases
CDD, VBCH, DAND6, SOST1
Gene ID
50964
Swiss Prot
Q9BQB4
Accession Number
NP_079513
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Pig, Rabbit
Immunogen
The immunogen is a synthetic peptide directed towards the following sequence ASCKCKRLTRFHNQSELKDFGTEAARPQKGRKPRPRARSAKANQAELENA
Target
Sclerostin is a secreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain and sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. Loss-of-function mutations in this gene are associated with an autosomal-recessive disorder, sclerosteosis, which causes progressive bone overgrowth. A deletion downstream of this gene, which causes reduced sclerostin expression, is associated with a milder form of the disorder called van Buchem disease.
Partner Proteins
LRP6; LRP5
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 85%; Dog: 100%; Human: 100%; Mouse: 92%; Pig: 92%; Rabbit: 92%; Rat: 100%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
24 kDa
Shipping Conditions
Wet Ice
Protein Length
213
NCBI Gene Symbol
SOST
NCBI GB Accession Number
SOST
Host or Source
Rabbit
Protein Name
Sclerostin
Nucleotide Accession Number
NM_025237
Peptide Sequence
ASCKCKRLTRFHNQSELKDFGTEAARPQKGRKPRPRARSAKANQAELENA
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