SPHK1 Antibody - middle region : FITC (ARP63467_P050-FITC)
Product Specifications
Gene Name
Sphingosine kinase 1
Gene Aliases
SPHK
Gene ID
8877
Swiss Prot
Q9NYA1
Accession Number
NP_001136073
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit
Target
The protein encoded by this gene catalyzes the phosphorylation of sphingosine to form sphingosine-1-phosphate (S1P), a lipid mediator with both intra- and extracellular functions. Intracellularly, S1P regulates proliferation and survival, and extracellularly, it is a ligand for cell surface G protein-coupled receptors. This protein, and its product S1P, play a key role in TNF-alpha signaling and the NF-kappa-B activation pathway important in inflammatory, antiapoptotic, and immune processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Partner Proteins
UBC; BIRC3; MBTPS1; TRAF6; RARG; EP300; SPHKAP; RPS6KC1; CTNND2; TRAF2; LYN; FYN; CTSB
Clonality
Polyclonal
Conjugation
FITC: Fluorescein Isothiocyanate
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 93%; Dog: 93%; Goat: 77%; Guinea Pig: 86%; Horse: 86%; Human: 100%; Mouse: 100%; Rabbit: 93%; Rat: 93%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
42kDa
Shipping Conditions
Wet Ice
Product Datasheet
Anti-SPHK1 (ARP63467_P050-FITC) antibody
Protein Length
384
NCBI Gene Symbol
SPHK1
NCBI GB Accession Number
SPHK1
Host or Source
Rabbit
Protein Name
Sphingosine kinase 1
Nucleotide Accession Number
NM_001142601
Peptide Sequence
DVDLESEKYRRLGEMRFTLGTFLRLAALRTYRGRLAYLPVGRVGSKTPAS
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