Dgat1 Antibody - N-terminal region : Biotin (ARP63409_P050-Biotin)
Selected Variant
ARP63409_P050-Biotin
Size: 100 µL
Product Specifications
Gene Name
Diacylglycerol O-acyltransferase 1
Gene Aliases
ARAT, Dgat, C75990, D15Ertd23, D15Ertd23e
Gene ID
13350
Swiss Prot
Q9Z2A7
Accession Number
NP_034176
Host
Rabbit
Reactivity
Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Pig, Rabbit, Sheep, Zebrafish
Immunogen
The immunogen is a synthetic peptide directed towards the N-terminal region of Mouse Dgat1
Target
Dgat1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. It may be involved in VLDL (very low density lipoprotein) assembly. In liver, Dgat1 plays a role in esterifying exogenous fatty acids to glycerol. It functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.
Clonality
Polyclonal
Conjugation
Biotin
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/ml
Homology
Cow: 100%; Dog: 93%; Goat: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 86%
Format
Liquid. Purified antibody supplied in 1x PBS buffer.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
57kDa
Shipping Conditions
Wet Ice
Protein Length
498
NCBI Gene Symbol
DGAT1
NCBI GB Accession Number
Dgat1
Host or Source
Rabbit
Protein Name
Diacylglycerol O-acyltransferase 1
Nucleotide Accession Number
NM_010046
Peptide Sequence
HRLQDSLFSSDSGFSNYRGILNWCVVMLILSNARLFLENLIKYGILVDPI
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