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CD1C Antibody - C-terminal region : FITC (ARP63373_P050-FITC)

Selected Variant

ARP63373_P050-FITC

Size: 100 µL

Product Specifications

Gene Aliases

R7, CD1, CD1A, BDCA1

Gene ID

911

Swiss Prot

P29017

Accession Number

NP_001756

Host

Rabbit

Reactivity

Human, Rat

Immunogen

The immunogen is a synthetic peptide directed towards the C-terminal region of Human CD1C

Target

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known.

Clonality

Polyclonal

Conjugation

FITC: Fluorescein Isothiocyanate

Type

Polyclonal Antibody

Applications

WB

Purification

Affinity Purified

Concentration

0.5 mg/ml

Homology

Human: 100%; Rat: 86%

Format

Liquid. Purified antibody supplied in 1x PBS buffer.

Reconstitution

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

Molecular Weight

35kDa

Shipping Conditions

Wet Ice

Protein Length

333

NCBI Gene Symbol

CD1C

NCBI GB Accession Number

CD1C

Host or Source

Rabbit

Protein Name

T-cell surface glycoprotein CD1c

Nucleotide Accession Number

NM_001765

Peptide Sequence

ASGFYPKPVWVTWMRNEQEQLGTKHGDILPNADGTWYLQVILEVASEEPA

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