CD274 Antibody - C-terminal region: HRP (ARP63362_P050-HRP)
Product Specifications
Gene Aliases
B7-H, B7H1, PDL1, PD-L1, hPD-L1, PDCD1L1, PDCD1LG1
Gene ID
29126
Swiss Prot
Q9NZQ7
Accession Number
NP_054862
Host
Rabbit
Reactivity
Human, Horse
Immunogen
The immunogen is a synthetic peptide directed towards the C-terminal region of CD274
Target
CD274 is involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.
Partner Proteins
PDCD1; CD80; PTPN11
Clonality
Polyclonal
Conjugation
HRP: Horseradish Peroxidase
Type
Polyclonal Antibody
Applications
WB
Purification
Affinity Purified
Concentration
0.5 mg/mL
Homology
Horse: 82%; Human: 100%
Format
Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.
Reconstitution
All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.
Molecular Weight
32kDa
Shipping Conditions
Wet Ice
Protein Length
290
NCBI Gene Symbol
CD274
Protein Name
Programmed cell death 1 ligand 1
Nucleotide Accession Number
NM_014143
Curated Selection
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